BDBM50400526 CHEMBL2204937

SMILES Cc1nc(no1)[C@]1(N[C@@H](Cc2c1[nH]c1ccccc21)c1nc(c[nH]1)-c1ccc(F)cc1)c1cnn(C)c1

InChI Key InChIKey=NTIFDLOQPKMIJK-UHFFFAOYSA-N

Data  1 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50400526   

TargetSomatostatin receptor type 3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50400526(CHEMBL2204937)
Affinity DataIC50: 3.60nMAssay Description:Inhibition of human SSTR3 transfected in CHO cells assessed as inhibition of SRIF-induced reduction of cAMP accumulation after 45 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSomatostatin receptor type 3(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50400526(CHEMBL2204937)
Affinity DataIC50: 4.80nMAssay Description:Inhibition of mouse SSTR3 transfected in CHO cells assessed as inhibition of SRIF-induced reduction of cAMP accumulation after 45 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSomatostatin receptor type 3(Mouse)
TBA

Curated by ChEMBL
LigandPNGBDBM50400526(CHEMBL2204937)
Affinity DataIC50: 1.20nMAssay Description:Displacement of [125I]SS-28 from mouse SSTR3 transfected in CHO cells after 60 to 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSomatostatin receptor type 3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50400526(CHEMBL2204937)
Affinity DataIC50: 2.30nMAssay Description:Displacement of [125I]SS-28 from human SSTR3 transfected in CHO cells after 60 to 90 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50400526(CHEMBL2204937)
Affinity DataKi:  462nMAssay Description:Displacement of radiolabeled MK-499 from human ERG channelMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed