BDBM50400299 CHEMBL2181316

SMILES C1CC=CCOc2cccc(Nc3nccc(n3)-c3cccc(O1)c3)c2

InChI Key InChIKey=WVCWTIZSQNCNBU-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50400299   

LigandPNGBDBM50400299(CHEMBL2181316)
Affinity DataIC50: 70nMAssay Description:Inhibition of recombinant TYK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50400299(CHEMBL2181316)
Affinity DataIC50: 230nMAssay Description:Inhibition of recombinant JAK2 using Poly (Glu,Ala,Tyr) as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50400299(CHEMBL2181316)
Affinity DataIC50: 880nMAssay Description:Inhibition of recombinant FLT3 using Poly (Glu,Ala,Tyr) as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50400299(CHEMBL2181316)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant JAK3 using Poly (Glu,Ala,Tyr) as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK1(Human)
S*Bio

Curated by ChEMBL
LigandPNGBDBM50400299(CHEMBL2181316)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant JAK1 using Poly (Glu,Ala,Tyr) as substrate after 2 hrs by luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed