BDBM50400275 CHEMBL2180766::US9085555, 127

SMILES CC(C)(C)OC(=O)Cc1ccc2c(NC(=O)N3[C@@H]4C[C@@H]4C[C@H]3C(=O)NCc3cccc(Cl)c3F)cn(C(N)=O)c2c1

InChI Key InChIKey=ITTNDCXUUDNAPV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50400275   

TargetComplement factor D(Human)
Novartis

US Patent
LigandPNGBDBM50400275(CHEMBL2180766 | US9085555, 127)
Affinity DataIC50: 3nMpH: 7.5 T: 2°CAssay Description:Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compound at vario...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details
Go to US Patent

TargetComplement factor D(Human)
Novartis

US Patent
LigandPNGBDBM50400275(CHEMBL2180766 | US9085555, 127)
Affinity DataIC50: 3nMAssay Description:Inhibition of recombinant human complement factor D after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed