BDBM50400274 CHEMBL2180765::US9085555, 373

SMILES NC(=O)n1cc(NC(=O)N2[C@@H]3C[C@@H]3C[C@H]2C(=O)NCc2cccc(Cl)c2F)c2cc(OCC#N)ccc12

InChI Key InChIKey=SOCAXRLFGRNEPK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50400274   

TargetComplement factor D(Human)
Novartis

US Patent
LigandPNGBDBM50400274(CHEMBL2180765 | US9085555, 373)
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:Recombinant human factor D (expressed in E. coli and purified using standard methods) at 10 nM concentration is incubated with test compound at vario...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/14/2016
Entry Details
Go to US Patent

TargetComplement factor D(Human)
Novartis

US Patent
LigandPNGBDBM50400274(CHEMBL2180765 | US9085555, 373)
Affinity DataIC50: 1nMAssay Description:Inhibition of recombinant human complement factor D after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed