BDBM50400063 CHEMBL2177744::US11191732, Example 4

SMILES O=C(CCCCc1nnc(NC(=O)Cc2ccccc2)s1)NCCN1CCCC1

InChI Key InChIKey=UPLGSCROHQZZQN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50400063   

TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50400063(CHEMBL2177744 | US11191732, Example 4)
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of human kidney glutaminase (124 to 669) using L-[3H]-glutamine as substrate after 45 mins by GLS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetGlutaminase kidney isoform, mitochondrial(Human)
Johns Hopkins University

Curated by ChEMBL
LigandPNGBDBM50400063(CHEMBL2177744 | US11191732, Example 4)
Affinity DataIC50: 4.60E+3nMAssay Description:A high throughput screening (HTS) assay and together with NCATS screened over 350,000 compounds in attempt to identify novel GLS inhibitor structures...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/17/2022
Entry Details
Go to US Patent