BDBM50400035 CHEMBL2177735::US9169259, I-84

SMILES CC1CCCN1c1cccc(Nc2cc(nn3ccnc23)-c2cccc(CN)c2)n1

InChI Key InChIKey=SGEVJGXOSCBSTO-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50400035   

TargetTyrosine-protein kinase SYK [360-635](Human)
Hoffmann-La Roche

US Patent
LigandPNGBDBM50400035(CHEMBL2177735 | US9169259, I-84)
Affinity DataIC50: 15.6nMAssay Description:Assay plates: 96-well MultiScreen 0.65 um filter plates (Millipore Cat. No.: MADVNOB10)Streptavidin coated beads: Streptavidin Sepharose, suspension ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2016
Entry Details
Go to US Patent

TargetTyrosine-protein kinase SYK(Human)
Hoffmann-La Roche

Curated by ChEMBL
LigandPNGBDBM50400035(CHEMBL2177735 | US9169259, I-84)
Affinity DataIC50: 16nMAssay Description:Inhibition of human recombinant spleen tyrosine kinase (360 to 635 amino acid residues) after 10 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed