BDBM50399952 CHEMBL2181222

SMILES Clc1cccc(Oc2ccncc2C(=O)N2CCN(C3CC3)c3ccccc23)c1

InChI Key InChIKey=UMJJEAJBZJJYQD-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50399952   

TargetG-protein coupled bile acid receptor 1(Mouse)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50399952(CHEMBL2181222)
Affinity DataEC50:  31nMAssay Description:Agonist activity at mouse TGR5 expressed in HEK293 cells incubated for 5.5 hrs by CRE-driven luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetG-protein coupled bile acid receptor 1(Human)
Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50399952(CHEMBL2181222)
Affinity DataEC50:  7.90nMAssay Description:Agonist activity at human TGR5 expressed in HEK293 cells incubated for 5.5 hrs by CRE-driven luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed