BDBM50399885 CHEMBL2180640

SMILES CCCCN(CCc1ccccc1)CCc1cccc(O)c1

InChI Key InChIKey=SDERQNAMIWOFFX-UHFFFAOYSA-N

Data  9 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50399885   

TargetKappa-type opioid receptor(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50399885(CHEMBL2180640)
Affinity DataEC50:  46nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cell membranes incubated for 60 mins by [35S]GTPgammaS binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50399885(CHEMBL2180640)
Affinity DataKi:  11nMAssay Description:Displacement of [3H]U69,593 from human kappa opioid receptor expressed in CHO cell membranes incubated for 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50399885(CHEMBL2180640)
Affinity DataKi:  11nMAssay Description:Binding affinity to KOR (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50399885(CHEMBL2180640)
Affinity DataKi:  360nMAssay Description:Binding affinity to MOR (unknown origin) assessed as inhibition constant by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetMu-type opioid receptor(Human)
University of Mississippi

Curated by ChEMBL
LigandPNGBDBM50399885(CHEMBL2180640)
Affinity DataKi:  412nMAssay Description:Displacement of [3H]DAMGO from human mu opioid receptor expressed in CHO cell membranes incubated for 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetD(3) dopamine receptor(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50399885(CHEMBL2180640)
Affinity DataKi:  1.15E+3nMAssay Description:Displacement of [3H]YM-09151-2 from human dopamine D3 receptor expressed in CHOp cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetD(2) dopamine receptor(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50399885(CHEMBL2180640)
Affinity DataKi:  1.23E+3nMAssay Description:Displacement of [3H]YM-09151-2 from human dopamine D2 receptor expressed in CHOp cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50399885(CHEMBL2180640)
Affinity DataKi:  2.43E+3nMAssay Description:Displacement of [3H]pCl-DPDPE from human delta opioid receptor expressed in CHO cell membranes incubated for 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50399885(CHEMBL2180640)
Affinity DataKi:  2.70E+3nMAssay Description:Binding affinity to DOR (unknown origin) assessed as inhibition constant by ratio ligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/18/2024
Entry Details
PubMed
TargetD(1A) dopamine receptor(Human)
University of Innsbruck

Curated by ChEMBL
LigandPNGBDBM50399885(CHEMBL2180640)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]SCH-23390 from human dopamine D1 receptor expressed in LHD1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed