BDBM50399824 CHEMBL2180259

SMILES Cc1c(oc2c(Cl)cccc12)C(=O)N[C@@H]1C2CCN(CC2)[C@H]1Cc1cccnc1

InChI Key InChIKey=TTYPEICBBIVUBR-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50399824   

LigandPNGBDBM50399824(CHEMBL2180259)
Affinity DataEC50:  8.20E+3nMAssay Description:Agonist activity at rat alpha7 nAchR expressed in GH4C1 cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50399824(CHEMBL2180259)
Affinity DataKi:  352nMAssay Description:Displacement of [3H]epibatidine form human alpha7 nAchR expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50399824(CHEMBL2180259)
Affinity DataKi:  980nMAssay Description:Displacement of [3H]nicotine human alpha4beta2 nAChR in SH-EP1 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed