BDBM50399768 CHEMBL2180252

SMILES Cc1ccc2cc(oc2c1)C(=O)N[C@@H]1C2CCN(CC2)[C@H]1Cc1cccnc1

InChI Key InChIKey=STZQGKJXRVFJDJ-UHFFFAOYSA-N

Data  2 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50399768   

LigandPNGBDBM50399768(CHEMBL2180252)
Affinity DataEC50:  110nMAssay Description:Agonist activity at rat alpha7 nAchR expressed in GH4C1 cells by whole cell patch clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50399768(CHEMBL2180252)
Affinity DataKi:  5.5nMAssay Description:Displacement of [3H]epibatidine form human alpha7 nAchR expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50399768(CHEMBL2180252)
Affinity DataKi:  1.50E+3nMAssay Description:Displacement of [3H]nicotine human alpha4beta2 nAChR in SH-EP1 cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed