BDBM50399405 CHEMBL2178286::US8623865, 2

SMILES CCc1ccc(Oc2ccc(cc2F)C(=O)N2CCNC(=O)C2)c(O)c1

InChI Key InChIKey=WUOZMZMHRFAYPT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50399405   

TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus (strain NCTC 8325 / PS 47))
Fab Pharma

US Patent
LigandPNGBDBM50399405(CHEMBL2178286 | US8623865, 2)
Affinity DataIC50: 29nMpH: 6.5Assay Description:The assay buffer AB contained 50 mM ADA (N-(2-acetamido)iminodiacetic acid monosodium salt) pH 6.5, 1 mM dithiothreitol, 0.006% Triton-X100 and 50 mM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/22/2014
Entry Details
Go to US Patent

TargetEnoyl-[acyl-carrier-protein] reductase [NADPH] FabI(Staphylococcus aureus (strain MRSA252))
Mutabilis

Curated by ChEMBL
LigandPNGBDBM50399405(CHEMBL2178286 | US8623865, 2)
Affinity DataIC50: 28nMAssay Description:Inhibition of Staphylococcus aureus recombinant FabI using trans-2-octenoyl N-acetylcysteamine thioester as substrate preincubated for 60 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed