BDBM50399277 CHEMBL2180553

SMILES Oc1nc(N=NCc2ccccc2O)sc1CC(=O)Nc1cccc(c1)C(F)(F)F

InChI Key InChIKey=KIGOWWJXMRPCFO-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50399277   

TargetThymidylate synthase(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50399277(CHEMBL2180553)
Affinity DataIC50: 9.00E+4nMAssay Description:Inhibition of human thymidylate synthase expressed in Escherichia coli incubated for 1 hr by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50399277(CHEMBL2180553)
Affinity DataKi:  1.30E+3nMAssay Description:Inhibition of human thymidylate synthase expressed in Escherichia coli incubated for 1 hr using varying mTHF levels by spectrophotometry based Linewe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetThymidylate synthase(Human)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM50399277(CHEMBL2180553)
Affinity DataKi:  2.50E+3nMAssay Description:Inhibition of human thymidylate synthase expressed in Escherichia coli incubated for 1 hr using varying dUMP levels by spectrophotometry based Linewe...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed