BDBM50399077 CHEMBL2179306

SMILES NS(=O)(=O)c1ccc(cc1)-n1ncc2CSc3cc(ccc3-c12)C(F)(F)F

InChI Key InChIKey=UIWAHXLXRURYJZ-UHFFFAOYSA-N

Data  15 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 50399077   

TargetCarbonic anhydrase 2(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50399077(CHEMBL2179306)
Affinity DataKi:  210nMAssay Description:Inhibition of human recombinant full length CA2 pre-incubated for 15 mins by stopped-flow CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50399077(CHEMBL2179306)
Affinity DataKi:  238nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant carbonic anhydrase Rv3273 pre-incubated for 15 mins by stopped-flow CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50399077(CHEMBL2179306)
Affinity DataKi:  318nMAssay Description:Inhibition of human recombinant full length CA1 pre-incubated for 15 mins by stopped-flow CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 5A, mitochondrial(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50399077(CHEMBL2179306)
Affinity DataKi:  327nMAssay Description:Inhibition of human recombinant full length CA5A pre-incubated for 15 mins by stopped-flow CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50399077(CHEMBL2179306)
Affinity DataKi:  357nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant carbonic anhydrase Rv3588c pre-incubated for 15 mins by stopped-flow CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 14(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50399077(CHEMBL2179306)
Affinity DataKi:  548nMAssay Description:Inhibition of human recombinant CA14 catalytic domain pre-incubated for 15 mins by stopped-flow CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBeta-carbonic anhydrase 1(Mycobacterium tuberculosis (strain ATCC 25618 / H3...)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50399077(CHEMBL2179306)
Affinity DataKi:  613nMAssay Description:Inhibition of Mycobacterium tuberculosis recombinant carbonic anhydrase Rv1284 pre-incubated for 15 mins by stopped-flow CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 7(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50399077(CHEMBL2179306)
Affinity DataKi:  628nMAssay Description:Inhibition of human recombinant full length CA7 pre-incubated for 15 mins by stopped-flow CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 13(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50399077(CHEMBL2179306)
Affinity DataKi:  714nMAssay Description:Inhibition of human recombinant CA13 catalytic domain pre-incubated for 15 mins by stopped-flow CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 9(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50399077(CHEMBL2179306)
Affinity DataKi:  2.57E+3nMAssay Description:Inhibition of human recombinant CA9 catalytic domain pre-incubated for 15 mins by stopped-flow CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 5B, mitochondrial(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50399077(CHEMBL2179306)
Affinity DataKi:  3.25E+3nMAssay Description:Inhibition of human recombinant full length CA5B pre-incubated for 15 mins by stopped-flow CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 12(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50399077(CHEMBL2179306)
Affinity DataKi:  6.76E+3nMAssay Description:Inhibition of human recombinant CA12 catalytic domain pre-incubated for 15 mins by stopped-flow CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50399077(CHEMBL2179306)
Affinity DataKi:  7.14E+3nMAssay Description:Inhibition of human recombinant full length CA4 pre-incubated for 15 mins by stopped-flow CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50399077(CHEMBL2179306)
Affinity DataKi:  9.34E+3nMAssay Description:Inhibition of human recombinant full length CA6 pre-incubated for 15 mins by stopped-flow CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCarbonic anhydrase 3(Human)
University of Pisa

Curated by ChEMBL
LigandPNGBDBM50399077(CHEMBL2179306)
Affinity DataKi:  2.86E+4nMAssay Description:Inhibition of human recombinant full length CA3 pre-incubated for 15 mins by stopped-flow CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed