BDBM50398754 CHEMBL2179654

SMILES CN1CC[C@@]23[C@H]4Oc5c2c(C[C@@H]1[C@@]3(Cc1cc(cnc41)-c1ccc(Cl)cc1)OCc1ccccc1)ccc5O

InChI Key InChIKey=YYSCTYIWGJPHIQ-UHFFFAOYSA-N

Data  3 KI  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50398754   

TargetDelta-type opioid receptor(Human)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50398754(CHEMBL2179654)
Affinity DataEC50:  11nMAssay Description:Agonist activity at delta opioid receptor expressed in rat/mouse NG108-15 cells assessed as [35S]GTPgammaS binding by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50398754(CHEMBL2179654)
Affinity DataEC50:  301nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cells assessed as [35S]GTPgammaS binding by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50398754(CHEMBL2179654)
Affinity DataEC50:  215nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cells assessed as [35S]GTPgammaS binding by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50398754(CHEMBL2179654)
Affinity DataKi:  1.80nMAssay Description:Displacement of [3H]DADLE from human delta opioid receptor expressed in CHO cells by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50398754(CHEMBL2179654)
Affinity DataKi:  4.70nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cells assessed as [35S]GTPgammaS binding by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50398754(CHEMBL2179654)
Affinity DataKi:  49nMAssay Description:Displacement of [3H]U69,593 from human kappa opioid receptor expressed in CHO cells by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed