BDBM50398753 CHEMBL2179658

SMILES Oc1ccc2C[C@H]3N(CC4CC4)CC[C@@]45[C@@H](Oc1c24)c1ncc(cc1C[C@@]35OC(=O)Cc1ccccc1)-c1ccc(Cl)cc1

InChI Key InChIKey=RDEXMUKWTMRQJX-UHFFFAOYSA-N

Data  3 KI  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50398753   

TargetKappa-type opioid receptor(Human)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50398753(CHEMBL2179658)
Affinity DataEC50:  26nMAssay Description:Agonist activity at human kappa opioid receptor expressed in CHO cells assessed as [35S]GTPgammaS binding by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50398753(CHEMBL2179658)
Affinity DataKi:  1nMAssay Description:Agonist activity at human mu opioid receptor expressed in CHO cells assessed as [35S]GTPgammaS binding by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50398753(CHEMBL2179658)
Affinity DataKi:  1.30nMAssay Description:Displacement of [3H]DADLE from human delta opioid receptor expressed in CHO cells by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetKappa-type opioid receptor(Human)
Southern Research Institute

Curated by ChEMBL
LigandPNGBDBM50398753(CHEMBL2179658)
Affinity DataKi:  3.10nMAssay Description:Displacement of [3H]U69,593 from human kappa opioid receptor expressed in CHO cells by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed