BDBM50398714 CHEMBL2178742

SMILES COc1ccc(cc1NC1CCN(C)CC1)S(=O)(=O)N1CCOc2ccc(Cl)cc12

InChI Key InChIKey=XEDMJQGYEUEUJR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50398714   

TargetCytochrome P450 3A4(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50398714(CHEMBL2178742)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibition of CYP3A4 in human liver microsomes using midazolam as substrate after 5 mins by LC-MS/MS analysis in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Suven Life Sciences

Curated by ChEMBL
LigandPNGBDBM50398714(CHEMBL2178742)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of CYP2D6 in human liver microsomes using dextromethorphan as substrate after 10 mins by LC-MS/MS analysis in presence of NADPHMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed