BDBM50398364 CHEMBL2177369

SMILES C[C@@H]1C[C@@H](O)c2ncnc(N3CCN(CC3)C(=O)[C@H]([C@@H]3CCCCN3)c3ccc(Cl)cc3)c12

InChI Key InChIKey=XLELDVURKKAFNR-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50398364   

TargetRAC-alpha serine/threonine-protein kinase(Human)
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50398364(CHEMBL2177369)
Affinity DataIC50: 9nMAssay Description:Competitive inhibition of wild-type full-length amino-terminal polyhistidine-tagged human Akt1 expressed in recombinant baculovirus system using fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50398364(CHEMBL2177369)
Affinity DataIC50: 530nMAssay Description:Competitive inhibition of wild-type full-length amino-terminal polyhistidine-tagged human Akt1 expressed in recombinant baculovirus system using fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetRAC-gamma serine/threonine-protein kinase(Human)
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50398364(CHEMBL2177369)
Affinity DataIC50: 12nMAssay Description:Competitive inhibition of wild-type full-length amino-terminal polyhistidine-tagged human Akt3 expressed in recombinant baculovirus system using fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetRAC-beta serine/threonine-protein kinase(Human)
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50398364(CHEMBL2177369)
Affinity DataIC50: 22nMAssay Description:Competitive inhibition of wild-type full-length amino-terminal polyhistidine-tagged human Akt2 expressed in recombinant baculovirus system using fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed