BDBM50398360 CHEMBL2178597

SMILES C[C@@H]1C[C@@H](O)c2ncnc(N3CCN(CC3)C(=O)[C@H](CNC(C)(C)C)c3ccc(c(F)c3)C(F)(F)F)c12

InChI Key InChIKey=OSDYJCFGRBVWAT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50398360   

TargetRAC-alpha serine/threonine-protein kinase(Human)
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50398360(CHEMBL2178597)
Affinity DataIC50: 3nMAssay Description:Competitive inhibition of wild-type full-length amino-terminal polyhistidine-tagged human Akt1 expressed in recombinant baculovirus system using fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50398360(CHEMBL2178597)
Affinity DataIC50: 92nMAssay Description:Competitive inhibition of wild-type full-length amino-terminal polyhistidine-tagged human Akt1 expressed in recombinant baculovirus system using fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetRAC-gamma serine/threonine-protein kinase(Human)
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50398360(CHEMBL2178597)
Affinity DataIC50: 3nMAssay Description:Competitive inhibition of wild-type full-length amino-terminal polyhistidine-tagged human Akt3 expressed in recombinant baculovirus system using fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetRAC-beta serine/threonine-protein kinase(Human)
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50398360(CHEMBL2178597)
Affinity DataIC50: 5nMAssay Description:Competitive inhibition of wild-type full-length amino-terminal polyhistidine-tagged human Akt2 expressed in recombinant baculovirus system using fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed