BDBM50398079 CHEMBL2182018

SMILES CCCCNC(=O)CC[Si]([C@H](CC(C)C)NC(=O)[C@@H](NC(=O)Cc1ccc2ccccc2c1)[C@@H](C)CC)(c1ccccc1)c1ccccc1

InChI Key InChIKey=MMYMNEQKCCGWBV-UHFFFAOYSA-N

Data  1 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50398079   

TargetNeutrophil elastase(Human)
Aarhus University

Curated by ChEMBL
LigandPNGBDBM50398079(CHEMBL2182018)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of human neutrophil elastase assessed as hydrolysis of N-succinyl-Ala-Ala-Pro-Val-p-nitroanilide incubated for 2 hrs measured for 20 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProthrombin(Human)
Aarhus University

Curated by ChEMBL
LigandPNGBDBM50398079(CHEMBL2182018)
Affinity DataIC50: 9.20E+4nMAssay Description:Inhibition of thrombin assessed as hydrolysis of H-D-Pro-L-Phe-L-Arg-p-nitroanilide incubated for 2 hrs measured for 20 mins by microplate reader ana...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCathepsin G(Human)
Aarhus University

Curated by ChEMBL
LigandPNGBDBM50398079(CHEMBL2182018)
Affinity DataIC50: 1.20E+5nMAssay Description:Inhibition of cathepsin G assessed as hydrolysis of N-succinyl-Ala-Ala-Pro-Phe-p-nitroanilide incubated for 2 hrs measured for 20 mins by microplate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetNeutrophil elastase(Human)
Aarhus University

Curated by ChEMBL
LigandPNGBDBM50398079(CHEMBL2182018)
Affinity DataKi:  1.30E+4nMAssay Description:Noncompetitive inhibition of human neutrophil elastase assessed as hydrolysis of N-succinyl-Ala-Ala-Pro-Val-p-nitroanilide incubated for 2 hrs measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed