BDBM50398018 CHEMBL2180410

SMILES COCCc1ccc(cn1)-c1c(C)nc2c(nccn12)N1CCOCC1

InChI Key InChIKey=XVWPXHVWMMHZOG-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50398018   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rat)
Janssen Pharmaceutica

Curated by ChEMBL

LigandBDBM50398018(CHEMBL2180410)Copy SMILESCopy InChI

Affinity DataIC50: 182nMAssay Description:Inhibition of rat recombinant PDE10A expressed in Sf9 cells using [3H]cAMP substrate incubated for 60 mins by topcount scintillation counting methodMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
4/3/2016
Entry Details Article
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TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Rat)
Janssen Pharmaceutica

Curated by ChEMBL

LigandBDBM50398018(CHEMBL2180410)Copy SMILESCopy InChI

Affinity DataIC50: 190nMAssay Description:Inhibition of rat recombinant PDE10A2 expressed in baculovirus infected SF21 cells using [3H]cAMP as substrate after 60 mins by scintillation proximi...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPurchaseCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/17/2013
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL