BDBM50398005 CHEMBL2180430::US8691827, I-8

SMILES CC(C)CC(=O)N1CCc2nc(nc(N(C)Cc3ccccc3)c2C1)-c1cncc(c1)-c1cn[nH]c1

InChI Key InChIKey=IKVVLWDRBHJIRD-UHFFFAOYSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50398005   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50398005(CHEMBL2180430 | US8691827, I-8)
Affinity DataKi:  15nMAssay Description:The PDE10 Ki is a measure of the ability of the test compound to inhibit the action of the PDE10 enzyme. The final product may be further modified, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/30/2014
Entry Details
Go to US Patent

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Merck Sharp & Dohme

US Patent
LigandPNGBDBM50398005(CHEMBL2180430 | US8691827, I-8)
Affinity DataKi:  15nMAssay Description:Inhibition of PDE10A by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed