BDBM50397989 CHEMBL2180805::US8759532, 32

SMILES C1CN(CCO1)c1cccnc1Oc1ccc(Nc2nc3ccccc3s2)cc1

InChI Key InChIKey=IYBQVHPASLEZNE-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50397989   

TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Amgen

US Patent

LigandBDBM50397989(CHEMBL2180805 | US8759532, 32)Copy SMILESCopy InChI

Affinity DataIC50: 0.962nMT: 2°CAssay Description:To check the inhibition profile, 5 μL of serial diluted compounds were incubated with 5 μL of diluted PDE10 enzyme (BPS Bioscience, San Die...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
11/18/2014
Entry Details
Copy Entry DOIGo to US Patent

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TargetcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A(Human)
Amgen

US Patent

LigandBDBM50397989(CHEMBL2180805 | US8759532, 32)Copy SMILESCopy InChI

Affinity DataIC50: 0.960nMAssay Description:Inhibition of PDE10AMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/17/2013
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL