BDBM50397961 CHEMBL2179988

SMILES c1cc(cc(c1)NC(=O)/C=C/C(=O)O)C(=O)N

InChI Key InChIKey=GNFSYBNDPOBXLJ-UHFFFAOYSA-N

Data  7 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50397961   

TargetProtein mono-ADP-ribosyltransferase PARP15(Human)
Karolinska Institutet

Curated by ChEMBL
LigandPNGBDBM50397961(CHEMBL2179988)
Affinity DataIC50: 1.78E+4nMAssay Description:Inhibition of hexahistidine-tagged human recombinant ARTD7 catalytic domain (459 to 656 amino acids) expressed in Escherichia coli BL21(DE3) assessed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2016
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Karolinska Institutet

Curated by ChEMBL
LigandPNGBDBM50397961(CHEMBL2179988)
Affinity DataIC50: 3.63E+3nMAssay Description:Inhibition of hexahistidine-tagged full length human recombinant ARTD1 expressed in Escherichia coli BL21(DE3) assessed as Inhibition of ADP-ribosylt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2016
Entry Details Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP10(Human)
Karolinska Institutet

Curated by ChEMBL
LigandPNGBDBM50397961(CHEMBL2179988)
Affinity DataIC50: 1.38E+3nMAssay Description:Inhibition of hexahistidine-tagged full length human recombinant ARTD10 expressed in Escherichia coli BL21(DE3) assessed as Inhibition of ADP-ribosyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2016
Entry Details Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
Karolinska Institutet

Curated by ChEMBL
LigandPNGBDBM50397961(CHEMBL2179988)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of hexahistidine-tagged human recombinant ARTD8 catalytic domain (1611 to 1801 amino acids) expressed in Escherichia coli BL21(DE3) assess...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProtein mono-ADP-ribosyltransferase PARP10(Human)
Karolinska Institutet

Curated by ChEMBL
LigandPNGBDBM50397961(CHEMBL2179988)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of hexahistidine-tagged full length human recombinant ARTD10 expressed in Escherichia coli BL21(DE3) assessed as Inhibition of ADP-ribosyl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2016
Entry Details Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP15(Human)
Karolinska Institutet

Curated by ChEMBL
LigandPNGBDBM50397961(CHEMBL2179988)
Affinity DataIC50: 1.78E+4nMAssay Description:Inhibition of hexahistidine-tagged human recombinant ARTD7 catalytic domain (459 to 656 amino acids) expressed in Escherichia coli BL21(DE3) assessed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2016
Entry Details Article
PubMed
TargetPoly [ADP-ribose] polymerase 1(Human)
Karolinska Institutet

Curated by ChEMBL
LigandPNGBDBM50397961(CHEMBL2179988)
Affinity DataIC50: 3.60E+3nMAssay Description:Inhibition of hexahistidine-tagged full length human recombinant ARTD1 expressed in Escherichia coli BL21(DE3) assessed as Inhibition of ADP-ribosylt...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/28/2016
Entry Details Article
PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Human)
Karolinska Institutet

Curated by ChEMBL
LigandPNGBDBM50397961(CHEMBL2179988)
Affinity DataKd:  1.12E+4nMAssay Description:Binding affinity at human recombinant ARTD8 expressed in Escherichia coli BL21 (DE3) R3 pRARE cells by isothermal titration calorimetryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)