BDBM50397740 CHEMBL2181988

SMILES c1ccc2c(c1)[C@]3(CCNC3)C(=O)N2

InChI Key InChIKey=FQSHLSLQUHZOMV-UHFFFAOYSA-N

Data  1 IC50  1 Kd

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50397740   

TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50397740(CHEMBL2181988)
Affinity DataIC50: 1.10E+6nMAssay Description:Inhibition of recombinant BACE1 using NH-SEVNLAAEF-COOH as substrate after 30 mins by NMR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50397740(CHEMBL2181988)
Affinity DataKd:  1.40E+6nMAssay Description:Inhibition of recombinant BACE1 binding to biotinylated stat-val peptide after 6 mins by octet assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed