BDBM50397471 CHEMBL2169898

SMILES COc1cccc(c1)S(=O)(=O)Nc1ccc(cc1)N1CCN(CC1)c1cccc(c1)-c1c(C(=O)NCCCN2CCN(C)CC2)c(C)n(C)c1-c1ccc(Cl)cc1

InChI Key InChIKey=PKYQQOFXDYYXLL-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50397471   

TargetApoptosis regulator Bcl-2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50397471(CHEMBL2169898)
Affinity DataIC50: 802nMAssay Description:Inhibition of N-terminal 6xHis-tagged human Bcl-2 expressed in Escherichia coli BL21 (DE3) after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetApoptosis regulator Bcl-2(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50397471(CHEMBL2169898)
Affinity DataKi:  207nMAssay Description:Binding affinity to N-terminal 6xHis-tagged human Bcl-2 expressed in Escherichia coli BL21 (DE3) after 2 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed