BDBM50396632 CHEMBL2171937

SMILES Cn1c(CN2CCC(CC2)C(C)(C)O)nc2c(nc(nc12)-n1c(nc2ccccc12)N1CCOCC1)N1CCOCC1

InChI Key InChIKey=OPUFPYCKVQZHOP-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50396632   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Human)
Genentech

Curated by ChEMBL

LigandBDBM50396632(CHEMBL2171937)Copy SMILESCopy InChI

Affinity DataIC50: 39nMAssay Description:Inhibition of recombinant PI3Kdelta assessed as inhibition of PIP3 production for 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
5/17/2013
Entry Details Article
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