BDBM50396601 CHEMBL2171902

SMILES CN1c2ccc(O)cc2C(=C)c2ccccc2C1=O

InChI Key InChIKey=VGQGXKVPVNOLEN-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50396601   

TargetOxysterols receptor LXR-beta(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50396601(CHEMBL2171902)
Affinity DataIC50: 1.10E+4nMAssay Description:Transactivational antagonist activity at human LXRbeta transfected in HEK293 cells expressing CMX-Gal4N assessed as inhibition of T1317-induced lucif...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50396601(CHEMBL2171902)
Affinity DataIC50: 4.10E+3nMAssay Description:Antagonist activity at human LXR-alpha transfected in HEK293 cells after 16 hrs by luciferase reporter gene assay in presence of 0.3 uM N-(4-(1,1,1,3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2016
Entry Details Article
PubMed
TargetOxysterols receptor LXR-beta(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50396601(CHEMBL2171902)
Affinity DataIC50: 1.10E+4nMAssay Description:Antagonist activity at human LXR-beta transfected in HEK293 cells after 16 hrs by luciferase reporter gene assay in presence of 0.1 uM N-(4-(1,1,1,3,...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2016
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha/LXR-beta(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50396601(CHEMBL2171902)
Affinity DataIC50: 1.70E+3nMAssay Description:Transrepression activity of LXR in human THP1 cells assessed as inhibition of LPS-induced IL-6 level after 18 hrs by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/8/2016
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50396601(CHEMBL2171902)
Affinity DataIC50: 4.10E+3nMAssay Description:Transactivational antagonist activity at human LXRalpha transfected in HEK293 cells expressing CMX-Gal4N assessed as inhibition of T1317-induced luci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetOxysterols receptor LXR-alpha(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50396601(CHEMBL2171902)
Affinity DataIC50: 3.50E+3nMAssay Description:Antagonist activity at human LXRalpha expressed in HEK293T cells by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMed