BDBM50396556 CHEMBL2171398

SMILES Cc1ccccc1[C@H](CC(O)=O)NC(=O)c1cc(OCC2CC2)n(n1)-c1ccccc1F

InChI Key InChIKey=HEVPKOFLFHIHOI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50396556   

TargetCytochrome P450 3A4(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50396556(CHEMBL2171398)
Affinity DataIC50: 15nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetLysosomal protective protein(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50396556(CHEMBL2171398)
Affinity DataIC50: 15nMAssay Description:Inhibition of human recombinant Myc-His10-tagged cathepsin A expressed in baculovirus infected Sf9 cells using BodipyFL labeled bradykinin as substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetNeprilysin(Human)
Sanofi-Aventis Deutschland

Curated by ChEMBL
LigandPNGBDBM50396556(CHEMBL2171398)
Affinity DataIC50: 2.70E+4nMAssay Description:Inhibition of human recombinant NEP using Mca-RPPGFSAFK(Dnp)-OH as substrate incubated for 15 mins prior to substrate addition measured after 20 to 3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed