BDBM50396183 CHEMBL2172015

SMILES OP(O)(=O)Oc1ccc(Cc2oc(nc2C(=O)Nc2ccc(cc2)C2CCCCC2)-c2ccccc2)cc1

InChI Key InChIKey=MFIJMJQCUUNJCN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50396183   

TargetSignal transducer and activator of transcription 3(Human)
University of Central Florida Research Foundation

US Patent
LigandPNGBDBM50396183(CHEMBL2172015)
Affinity DataIC50: 3.30E+4nMAssay Description:A screening process evaluated in vitro disruption of STAT3(dimer)-DNA formation through a previously published EMSA based assays, giving a valuable i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2015
Entry Details
Go to US Patent

TargetSignal transducer and activator of transcription 3(Mouse)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50396183(CHEMBL2172015)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of STAT3 dimerization in v-Src transformed mouse NIH/3T3 cells overexpressing human EGFR assessed as suppression of STAT3-DNA interaction ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Human)
University of Central Florida Research Foundation

US Patent
LigandPNGBDBM50396183(CHEMBL2172015)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of recombinant STAT3 (unknown origin) expressed in baculovirus in Sf9 insect cells assessed as reduction in DNA binding activity with NIH3...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed