BDBM50396179 CHEMBL2172013

SMILES Cc1ccc(cc1)S(=O)(=O)OCC(=O)N(Cc1ccc(cc1)C1CCCCC1)c1ccc(C(O)=O)c(O)c1

InChI Key InChIKey=BKDNKNWZOBYQME-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50396179   

TargetSignal transducer and activator of transcription 3(Mouse)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50396179(CHEMBL2172013)
Affinity DataIC50: 4.30E+4nMAssay Description:Inhibition of STAT3 dimerization in v-Src transformed mouse NIH/3T3 cells overexpressing human EGFR assessed as suppression of STAT3-DNA interaction ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50396179(CHEMBL2172013)
Affinity DataIC50: 4.30E+4nMAssay Description:Binding affinity to Stat3 (unknown origin) using hSIE as probe preincubated for 30 mins followed by hSIE addition by electrophoretic mobility shift a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Human)
University of Toronto Mississauga

Curated by ChEMBL
LigandPNGBDBM50396179(CHEMBL2172013)
Affinity DataKi:  5.00E+4nMAssay Description:Inhibition of STAT3 SH2 domain assessed as inhibition of STAT3 SH2-phosphotyrosine interaction after 15 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed