BDBM50396174 CHEMBL2171899

SMILES [#6]-[#6]-[#8]-c1cc(\[#6]=[#6]-2/[#6](=O)-c3ccccc3-[#6]-2=O)cc(Cl)c1-[#8]-[#6]-c1cccc(c1)-[#6](-[#8])=O

InChI Key InChIKey=SKJUDOQRHKHVTJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50396174   

TargetSignal transducer and activator of transcription 3(Human)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50396174(CHEMBL2171899)
Affinity DataIC50: 1.44E+5nMAssay Description:Inhibition of IL6-mediated STAT3 phosphorylation in human HepG2 cells preincubated for 1 hr prior to IL6 challenge measured after 30 mins by immunobl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Human)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50396174(CHEMBL2171899)
Affinity DataIC50: 2.56E+5nMAssay Description:Inhibition of recombinant STAT3 assessed as inhibition of STAT3-phosphododecapeptide interaction by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed