BDBM50396172 CHEMBL2172008

SMILES CCN1C(=S)S\C(=C/c2ccc(o2)-c2ccc(cc2)C(O)=O)C1=O

InChI Key InChIKey=JCOCDHYTHMMUHD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50396172   

TargetSignal transducer and activator of transcription 3(Human)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50396172(CHEMBL2172008)
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of IL6-mediated STAT3 phosphorylation in human HepG2 cells preincubated for 1 hr prior to IL6 challenge measured after 30 mins by immunobl...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSignal transducer and activator of transcription 3(Human)
University of Southern California

Curated by ChEMBL
LigandPNGBDBM50396172(CHEMBL2172008)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of recombinant STAT3 assessed as inhibition of STAT3-phosphododecapeptide interaction by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed