BDBM50396149 CHEMBL2171744

SMILES CNc1nc(Nc2ccc(cc2OC)C(=O)N2CCOCC2)ncc1F

InChI Key InChIKey=KRGRTZALKQUTRT-UHFFFAOYSA-N

Data  3 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50396149   

LigandPNGBDBM50396149(CHEMBL2171744)
Affinity DataIC50: 418nMAssay Description:Inhibition of autophosphorylation of LRRK2 in human HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50396149(CHEMBL2171744)
Affinity DataKi:  58nMAssay Description:Inhibition of LRRK2 using FAM-LRRKtide as substrate after 120 mins by microfluidic capillary electrophoresis assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50396149(CHEMBL2171744)
Affinity DataKi:  71nMAssay Description:Inhibition of LRRK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50396149(CHEMBL2171744)
Affinity DataKi: >3.20E+3nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed