BDBM50396097 CHEMBL2170856

SMILES Oc1cccc(C(=O)Nc2cccc(NC(=O)c3cccc(O)c3O)c2)c1O

InChI Key InChIKey=MIQUEZGHEJGPJB-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50396097   

TargetTelomerase reverse transcriptase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50396097(CHEMBL2170856)
Affinity DataIC50: 670nMAssay Description:Inhibition of telomerase in human U937 cells by telomeric repeat amplification protocolMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50396097(CHEMBL2170856)
Affinity DataIC50: 1.28E+4nMAssay Description:Inhibition of telomerase in human HeLa cells using 5'-AAT CCG TCG AGC AGA GTT-3' as substrate incubated for 15 mins prior to extension reaction follo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50396097(CHEMBL2170856)
Affinity DataIC50: 1.21E+4nMAssay Description:Inhibition of telomerase in human HeLa cells using 5'-AAT CCG TCG AGC AGA GTT-3' as substrate incubated for 15 mins prior to extension reaction by te...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50396097(CHEMBL2170856)
Affinity DataIC50: 670nMAssay Description:Inhibition of human telomerase isolated from human U937 cellular extracts by SYBR Green staining-based TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50396097(CHEMBL2170856)
Affinity DataIC50: 230nMAssay Description:Inhibition of telomerase activity in human U2OS cell lysate measured after 24 hrs by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2019
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50396097(CHEMBL2170856)
Affinity DataIC50: 230nMAssay Description:Inhibition of telomerase activity in human MDA-MB-435 cell lysate measured after 24 hrs by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/6/2019
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50396097(CHEMBL2170856)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of telomerase (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed