BDBM50396072 CHEMBL2170583

SMILES CCOc1ccc(Nc2ncc(F)c(Nc3ccc(OCC)cc3)n2)cc1

InChI Key InChIKey=CAIIUUQRGUIPCF-UHFFFAOYSA-N

Data  2 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50396072   

TargetTyrosine-protein kinase SYK(Human)
Amarit Bioscience

Curated by ChEMBL
LigandPNGBDBM50396072(CHEMBL2170583)
Affinity DataEC50:  1.67E+3nMAssay Description:Inhibition of SYK in human mast cell cultures assessed as reduction in IgE-induced FCepsilonR1 mediated degranulation by tryptase release assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2016
Entry Details Article
PubMed
TargetTyrosine-protein kinase SYK(Human)
Amarit Bioscience

Curated by ChEMBL
LigandPNGBDBM50396072(CHEMBL2170583)
Affinity DataEC50:  1.67E+3nMAssay Description:Inhibition of SYK assessed as reduction in anti-IgE-mediated tryptase release by cell based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed