BDBM503956 US11034692, Compound 231::trans-N-(8-amino-6-(4-methylpyridin-3- yl)-2,7-naphthyridin-3-yl-2-(2- oxooxazolidin-5- yl)cyclopropanecarboxamide

SMILES Cc1ccncc1-c1cc2cc(NC(=O)[C@H]3C[C@@H]3C3CNC(=O)O3)ncc2c(N)n1

InChI Key InChIKey=DDVDXMMJLBUMNT-UHFFFAOYSA-N

Data  1 KI

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 503956   

TargetMitogen-activated protein kinase kinase kinase kinase 1(Human)
Genentech

US Patent

LigandBDBM503956(trans-N-(8-amino-6-(4-methylpyridin-3- yl)-2,7-nap...)Copy SMILESCopy InChI

Affinity DataKi:  0.173nMAssay Description:Lanth: For the binding assay, 4 ul 2×HPK1 and Eu-anti-GST antibody were added to each well of the assay plate using a Multidrop reagent dispenser. Th...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
12/5/2021
Entry Details
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