BDBM50395331 CHEMBL2164391

SMILES FC(F)(F)Cc1ccc(CNC(=O)C2N(CCc3ccccn3)C(=O)c3ccccc23)cc1

InChI Key InChIKey=HPSXNGYRKXICLD-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50395331   

TargetSodium channel protein type 5 subunit alpha(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50395331(CHEMBL2164391)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of human NaV1.5 alpha subunit expressed in CHOK1 cells at -90 mV holding potential by patch clamp electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
LigandPNGBDBM50395331(CHEMBL2164391)
Affinity DataIC50: 1.40E+4nMAssay Description:Binding affinity to human ERG expressed in CHOK1 cells by IonWorks HT assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSodium channel protein type 9 subunit alpha(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50395331(CHEMBL2164391)
Affinity DataIC50: 260nMAssay Description:Inhibition of recombinant human NaV1.7 alpha subunit expressed in HEK293 cells at -65 mV holding potential by patch clamp electrophysiological assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed