BDBM50395262 CHEMBL2163999

SMILES N[C@H]1CC[C@@H](CC1)Nc1cc(Nc2ccc(F)c(Cl)c2)n2nccc2n1

InChI Key InChIKey=ZDXQLMBSNKHXCJ-UHFFFAOYSA-N

Data  1 KI  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50395262   

LigandPNGBDBM50395262(CHEMBL2163999)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of MEK1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
Teijin Pharma

Curated by ChEMBL
LigandPNGBDBM50395262(CHEMBL2163999)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of GSK3betaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetTyrosine-protein kinase Lck(Human)
Teijin Pharma

Curated by ChEMBL
LigandPNGBDBM50395262(CHEMBL2163999)
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of LCKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 14(Human)
Teijin Pharma

Curated by ChEMBL
LigandPNGBDBM50395262(CHEMBL2163999)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of P38alphaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 5(Human)
Teijin Pharma

Curated by ChEMBL
LigandPNGBDBM50395262(CHEMBL2163999)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of PRAKMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Teijin Pharma

Curated by ChEMBL
LigandPNGBDBM50395262(CHEMBL2163999)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibition of ROK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMitogen-activated protein kinase 9(Human)
Teijin Pharma

Curated by ChEMBL
LigandPNGBDBM50395262(CHEMBL2163999)
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibition of JNK2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCyclin-dependent kinase 2(Human)
Teijin Pharma

Curated by ChEMBL
LigandPNGBDBM50395262(CHEMBL2163999)
Affinity DataIC50: 55nMAssay Description:Inhibition of CDK2 after 60 mins using [33P]-gamma-ATP by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Teijin Pharma

Curated by ChEMBL
LigandPNGBDBM50395262(CHEMBL2163999)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of MAPKAP-K2 using KKLNRTLSVA as substrate and [33P]-gamma-ATP after 30 mins by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMAP kinase-activated protein kinase 2(Human)
Teijin Pharma

Curated by ChEMBL
LigandPNGBDBM50395262(CHEMBL2163999)
Affinity DataKi:  6.00E+3nMAssay Description:Competitive inhibition of MAPKAP-K2 using KKLNRTLSVA as substrate and [33P]-gamma-ATP by Lineweaver-Burke plot analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed