BDBM50395149 CHEMBL2163572

SMILES CCC1COc2c(ccc3c2n1cc(C(=O)NC12CC4CC(CC(C4)C1)C2)c3=O)N1CCN(C)CC1

InChI Key

Data  4 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50395149   

TargetCannabinoid receptor 2(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50395149(CHEMBL2163572)
Affinity DataIC50: 196nMAssay Description:Agonist activity at human recombinant CB2 receptor expressed in CHO cell membranes assessed as inhibition of forskolin-induced cAMP accumulationMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50395149(CHEMBL2163572)
Affinity DataKi:  42nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB2 receptor expressed in CHO cell membranes incubated for 60 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCannabinoid receptor 2(Rat)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50395149(CHEMBL2163572)
Affinity DataKi:  61nMAssay Description:Displacement of [3H]CP-55940 from CB2 receptor in Sprague-Dawley rat spleen by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Rat)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50395149(CHEMBL2163572)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]CP-55940 from CB1 receptor in Sprague-Dawley rat brain by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCannabinoid receptor 1(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50395149(CHEMBL2163572)
Affinity DataKi: >1.00E+4nMAssay Description:Displacement of [3H]CP-55940 from human recombinant CB1 receptor expressed in CHO cell membranes incubated for 90 mins by scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed