BDBM50395062 CHEMBL2163914

SMILES COc1ccc(cc1)[C@H](NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](N)Cc1ccc(O)cc1)C(=C)C(N)=O

InChI Key InChIKey=WPWLYNPGSJQWTG-UHFFFAOYSA-N

Data  2 KI  2 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50395062   

TargetMu-type opioid receptor(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50395062(CHEMBL2163914)
Affinity DataEC50:  11nMAssay Description:Agonist activity at mu opioid receptor expressed in HEK293 cells assessed as inhibition of forskolin-induced cAMP accumulation after 30 mins by liqui...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Mouse)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50395062(CHEMBL2163914)
Affinity DataIC50: 299nMAssay Description:Agonist activity at delta opioid receptor in Kunming mouse vas deferens assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Guinea pig)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50395062(CHEMBL2163914)
Affinity DataIC50: 84nMAssay Description:Agonist activity at mu opioid receptor in guinea pig ileum assessed as inhibition of electrically-stimulated muscle contractionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetMu-type opioid receptor(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50395062(CHEMBL2163914)
Affinity DataKi:  4.80nMAssay Description:Displacement of [3H]DAMGO from FLAG-tagged mu opioid receptor expressed in HEK293 cells after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetDelta-type opioid receptor(Human)
Lanzhou University

Curated by ChEMBL
LigandPNGBDBM50395062(CHEMBL2163914)
Affinity DataKi:  1.02E+4nMAssay Description:Displacement of [3H]DPDPE from Myc-tagged delta opioid receptor expressed in HEK293 cells after 60 mins by liquid scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed