BDBM50394962 CHEMBL1394231

SMILES CCc1ccc(cc1)S(=O)(=O)c2c3nc(c4c(n3nn2)ccs4)NCc5cccs5

InChI Key InChIKey=UYFZCWXRMHSLTC-UHFFFAOYSA-N

Data  4 IC50

PDB links: 1 PDB ID matches this monomer.

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50394962   

TargetUrea transporter 1(Mouse)
San Francisco State University

Curated by ChEMBL
LigandPNGBDBM50394962(CHEMBL1394231)
Affinity DataIC50: 25.1nMAssay Description:Reversible inhibition of mouse UT-B-mediated urea transportMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetUrea transporter 1(Mouse)
San Francisco State University

Curated by ChEMBL
LigandPNGBDBM50394962(CHEMBL1394231)
Affinity DataIC50: 11nMAssay Description:Inhibition of UT-B in wild type CD1 mouse erythrocyte assessed as hemolysis after 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetUrea transporter 1(Human)
San Francisco State University

Curated by ChEMBL
LigandPNGBDBM50394962(CHEMBL1394231)
Affinity DataIC50: 11nMAssay Description:Inhibition of UT-B in human erythrocytes assessed as increase of hypotonic lysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetUrea transporter 1(Mouse)
San Francisco State University

Curated by ChEMBL
LigandPNGBDBM50394962(CHEMBL1394231)
Affinity DataIC50: 11nMAssay Description:Inhibition of UT-B in mouse acetamide-loaded erythrocyte assessed as increase of hypotonic lysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)