BDBM50394933 CHEMBL2165690

SMILES Cc1ccc(C[C@](NC(=O)NC2CCCC2)(c2cc(F)cc(c2)C(F)(F)F)c2ccc(Cl)cn2)cc1

InChI Key InChIKey=UEMDNULROJEQAH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50394933   

TargetCholesteryl ester transfer protein(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50394933(CHEMBL2165690)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of CETP-mediated [3H]cholesteryl ester transfer activity in human plasma after 2.5 hrs by scintillation counterMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetCholesteryl ester transfer protein(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50394933(CHEMBL2165690)
Affinity DataIC50: 23nMAssay Description:Inhibition of human recombinant CETP-mediated [3H]cholesteryl ester transfer from HDL to biotinylated LDL by scintillation proximity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed