BDBM50394774 CHEMBL2163385

SMILES [O-][N+](=O)c1ccc(CSc2cc3ccccc3[nH]2)c(c1)[N+]([O-])=O

InChI Key InChIKey=KKZWXRGXGSAWTN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50394774   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50394774(CHEMBL2163385)
Affinity DataIC50: 2.39E+4nMAssay Description:Inhibition of human 5-LOX in A23187-induced human whole blood assessed as reduction in LTB4 production pre-incubated for 20 mins before A23187 additi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50394774(CHEMBL2163385)
Affinity DataIC50: 800nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL2-DE3 incubated 10 mins before substrate addition by fluorescence spectrophotom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed