BDBM50394698 CHEMBL2165632

SMILES Cc1nc(N)sc1CCCNC(=N)NC(=O)CCCCCCCCC(=O)NC(=N)NCCCc1sc(N)nc1C

InChI Key InChIKey=LYEWBZFHFDTNJX-UHFFFAOYSA-N

Data  4 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50394698   

TargetHistamine H2 receptor(Guinea pig)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50394698(CHEMBL2165632)
Affinity DataEC50:  1.17nMAssay Description:Agonist activity at H2R in spontaneously beating guinea pig right atrium assessed as increase in heart rateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHistamine H2 receptor(Guinea pig)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50394698(CHEMBL2165632)
Affinity DataEC50:  0.390nMAssay Description:Agonist activity at guinea pig H2R-Gsalphas expressed in Sf9 cells at 0.1 nM to 10 uM by steady state GTPase activity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHistamine H2 receptor(Guinea pig)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50394698(CHEMBL2165632)
Affinity DataEC50:  0.390nMAssay Description:Agonist activity at guinea pig H2R-Gsalphas expressed in Sf9 cells at 0.1 nM to 10 uM by steady state GTPase activity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetHistamine H2 receptor(Human)
University of Regensburg

Curated by ChEMBL
LigandPNGBDBM50394698(CHEMBL2165632)
Affinity DataEC50:  7.76nMAssay Description:Agonist activity at human H2R-Gsalphas expressed in Sf9 cells at 0.1 nM to 10 uM by steady state GTPase activity assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed