BDBM50394631 CHEMBL2164594::US9169224, 28

SMILES O=C(Nc1ccccc1)N1CCN(Cc2cccc(Oc3ccccc3)c2)CC1

InChI Key InChIKey=XVWZNBHOIBWEOU-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50394631   

TargetFatty-acid amide hydrolase 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50394631(CHEMBL2164594 | US9169224, 28)
Affinity DataIC50: 80nMpH: 9.0Assay Description:Assay Method 1: T84 frozen pellets (contents of 1-4x15 cm culture dishes) were homogenized in 300 mL of FAAH assay buffer (125 mM Tris, 1 mM EDTA, 0....More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2016
Entry Details
Go to US Patent

TargetFatty-acid amide hydrolase 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50394631(CHEMBL2164594 | US9169224, 28)
Affinity DataIC50: 3.02E+3nMAssay Description:Inhibition of human recombinant FAAH expressed in COS7 cells using anandamide as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/27/2016
Entry Details Article
PubMed
LigandPNGBDBM50394631(CHEMBL2164594 | US9169224, 28)
Affinity DataIC50: 6.67E+3nMAssay Description:Inhibition of rat FAAH after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
Janssen Pharmaceutica

US Patent
LigandPNGBDBM50394631(CHEMBL2164594 | US9169224, 28)
Affinity DataIC50: 74nMAssay Description:Inhibition of human FAAH after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed