BDBM50394538 CHEMBL2159106

SMILES CC(C)c1n[nH]c(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c1Cc1ccc(O)cc1

InChI Key InChIKey=LZNSCJBZAOZHJT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50394538   

TargetSodium/glucose cotransporter 2(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50394538(CHEMBL2159106)
Affinity DataIC50: 285nMAssay Description:Inhibition of human SGLT2 expressed in COS7 cells assessed as reduction of [14C]-AMG uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50394538(CHEMBL2159106)
Affinity DataIC50: 207nMAssay Description:Inhibition of human SGLT1 expressed in COS7 cells assessed as reduction of [14C]-AMG uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50394538(CHEMBL2159106)
Affinity DataIC50: 285nMAssay Description:Inhibition of human SGLT2 expressed in COS7 cells assessed as inhibition [14C]-AMG cellular uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50394538(CHEMBL2159106)
Affinity DataIC50: 207nMAssay Description:Inhibition of human SGLT1 expressed in COS7 cells assessed as inhibition [14C]-AMG cellular uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed