BDBM50394533 CHEMBL2159101

SMILES CC(C)c1n[nH]c(O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)c1Cc1ccc(O)cc1C

InChI Key InChIKey=WVGZFGBLAOTZSN-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50394533   

TargetSodium/glucose cotransporter 2(Rat)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50394533(CHEMBL2159101)
Affinity DataIC50: 4.37E+3nMAssay Description:Inhibition of rat SGLT2 expressed in COS7 cells assessed as reduction of [14C]-AMG uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Rat)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50394533(CHEMBL2159101)
Affinity DataIC50: 183nMAssay Description:Inhibition of rat SGLT1 expressed in COS7 cells assessed as reduction of [14C]-AMG uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50394533(CHEMBL2159101)
Affinity DataIC50: 6.89E+3nMAssay Description:Inhibition of human SGLT2 expressed in COS7 cells assessed as reduction of [14C]-AMG uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Human)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50394533(CHEMBL2159101)
Affinity DataIC50: 320nMAssay Description:Inhibition of human SGLT1 expressed in COS7 cells assessed as reduction of [14C]-AMG uptakeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 2(Rat)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50394533(CHEMBL2159101)
Affinity DataIC50: 4.37E+3nMAssay Description:Inhibition of rat SGLT2More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetSodium/glucose cotransporter 1(Rat)
Kissei Pharmaceutical

Curated by ChEMBL
LigandPNGBDBM50394533(CHEMBL2159101)
Affinity DataIC50: 183nMAssay Description:Inhibition of rat SGLT1More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed