BDBM50394264 CHEMBL2159361

SMILES NC(=[NH2+])c1cccc(c1)S(=O)(=O)NCCCC(=O)Nc1cccc(c1)C(O)=O

InChI Key InChIKey=QXXWXTMTDJIQAI-UHFFFAOYSA-O

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50394264   

TargetTransmembrane protease serine 6(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50394264(CHEMBL2159361)
Affinity DataIC50: 5.00E+5nMAssay Description:Inhibition of human matriptase-2 expressed in HEK-MT2 cells using fluorogenic Boc- Gln-Ala-Arg-NH-Mec as substrate measured over 400 secs by spectrop...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetProthrombin(Human)
University of Bonn

Curated by ChEMBL
LigandPNGBDBM50394264(CHEMBL2159361)
Affinity DataKi:  7.50E+4nMAssay Description:Inhibition of human thrombin using fluorogenic Cbz-Gly-Gly-Arg-NH-Mec as substrate measured over 400 secs by spectrophotometryMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed