BDBM50393885 CHEMBL2158260

SMILES CC(C)Cn1cc2[C@H](CC(C)(C)Cc2n1)NCC(=O)[C@H](Cc1ccccc1)NC(C)=O

InChI Key InChIKey=WZKZELUAEMFHMD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50393885   

TargetBeta-secretase 1(Human)
Medivir

Curated by ChEMBL
LigandPNGBDBM50393885(CHEMBL2158260)
Affinity DataIC50: 290nMAssay Description:Inhibition of human BACE1 expressed in Escherichia coli BL21(DE3) using Eu-EVNLDAEFK as substrate incubated for 30 mins prior to substrate addition m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBeta-secretase 1(Human)
Medivir

Curated by ChEMBL
LigandPNGBDBM50393885(CHEMBL2158260)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of BACE1 in human HEK cells expressing APP Swedish mutant assessed as reduction in amyloid beta40 level by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed