BDBM50393835 CHEMBL2159733

SMILES CN1CCN(CCCNC(=O)c2c(C)n(C)c(c2-c2ccccc2)-c2ccc(Cl)cc2)CC1

InChI Key InChIKey=PUHZBGFCBZKWRB-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50393835   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50393835(CHEMBL2159733)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human N-terminal His8-tagged Mcl1 expressed in Escherichia coli BL21(DE3) assessed as inhibition of Fluorescein-labeled BID binding aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50393835(CHEMBL2159733)
Affinity DataIC50: 2.91E+5nMAssay Description:Inhibition of human N-terminal His8-tagged Bcl-XL expressed in Escherichia coli BL21(DE3) assessed as inhibition of Fluorescein-labeled BAK binding a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
University of Michigan

Curated by ChEMBL
LigandPNGBDBM50393835(CHEMBL2159733)
Affinity DataKi:  8.80E+4nMAssay Description:Inhibition of human N-terminal His8-tagged Bcl-XL expressed in Escherichia coli BL21(DE3) assessed as inhibition of Fluorescein-labeled BAK binding a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed